Table 2 Immunohistochemical staining showing semiquantitative scores across primary tumors and corresponding 2D and 3D models
Sample | Type | EMA | PR | Ki-67 | SSTR2 | GFAP | BC Overall | BC Best subclass | |
|---|---|---|---|---|---|---|---|---|---|
MO-38 | T | + 3 | + 1-+2 | 5%(10%) | + 3 | NS | MNG: 0.99 | Ben: 0.99 | 2: 0.91 |
2D | + 1 | 0-+1 | 95%(100%) | + 2-+3 | NS | NA | NA | NA | |
3D | + 3 | 0 | 5%(10%) | + 2 | NS | MNG: 0.98 | Ben: 0.77 | 2: 0.76 | |
MO-39 | T | + 1-+2 | + 2-+3 | 2–5%(20%) | + 3 | NS | MNG: 0.99 | Int: 0.76 | A: 0.76 |
2D | + 1 | + 2 | 15–30% | + 3 | NS | NA | NA | NA | |
3D | 0-+1 | + 1 | 2–5% | 0-+1 | NS | MNG: 0.98 | Ben: 0.91 | 1: 0.46 | |
MO-40 | T | + 3 | + 1 | 2–10%(20%) | + 2-+3 | NS | MNG: 0.99 | Ben: 0.99 | 1: 0.99 |
2D | 0-+1 | 0 | 2–10% | + 2 | NS | NA | NA | NA | |
3D | + 1 | 0 | 1–10% | + 1 | NS | MNG: 0.99 | Ben: 0.98 | 3: 0.87 | |
MO-41 | T | + 3 | 0 | 15–20%(30%) | + 3 | NS | MNG: 0.99 | Ben: 0.99 | 1: 0.99 |
2D | + 2 | 0 | 50–70% | + 2 | NS | NA | NA | NA | |
3D | + 1 | 0 | 10–20% | + 1-+2 | NS | MNG: 0.98 | Ben: 0.98 | 1: 0.98 | |
MO-42 | T | + 3 | + 2 | 5–10%(20%) | + 3 | NS | MNG: 0.99 | Ben: 0.89 | 2: 0.88 |
2D | + 1 | 0-+1 | 20–40% | + 1 | NS | NA | NA | NA | |
3D | + 3 | + 1 | 5–10% | + 2–3 | NS | MNG: 0.99 | Ben: 0.99 | 2: 0.96 | |
IOMM-Lee | 2D | 0 | 0 | 95–100% | 0 | NS | NA | NA | NA |
in vivo | 0 | 0 | 75–90% | 0 | NS | NA | NA | NA | |
3D | 0 | 0 | 50–90% | 0 | NS | NA | NA | NA | |