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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: Partial normalization of hippocampal oscillatory activity during sleep in TgF344-AD rats coincides with increased cholinergic synapses at early-plaque stage of Alzheimer’s disease

Fig. 4

Power and theta-gamma coupling in TgF344-AD rats during REM sleep. A) Mean normalized power spectra. Shading indicates SEM across the group. B) Averaged normalized power across distinct frequency bands of interest (+/- SEM). C) Comodulogram averaged across subjects demonstrating main frequencies of coupling. Color bar indicates the strength of the modulation index (MI) at different frequencies of theta (x-axis) and gamma (y-axis). D) Mean (+/- SEM) MI across subjects between theta-frequencies (6.5–9 Hz) and slow gamma frequencies (30–45 Hz). Dots represent subject MI values. E) Mean (+/- SEM) MI across subjects between theta frequencies (6.5-9HZ) and fast gamma frequencies 80–110 Hz. Dots represent subject MI values. gen = genotype, Hz = Hertz. * = p < 0.05, *** = p < 0.001

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Acta Neuropathologica Communications

ISSN: 2051-5960

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