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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: Oligodendrocyte-specific overexpression of human alpha-synuclein results in elevated MBP levels and inflammatory responses in TgM83 mice, mimicking the pathological features of multiple system atrophy

Fig. 2

Regional demyelination was observed in the injection side in TgM83 + AAVhSNCA group. a, b LFB shows areas with demyelination in the injection side of TgM83 + AAVhSNCA (arrow). Decreased LFB staining was shown on the injection side in TgM83 + AAVhSNCA, but not on the non-injection side, Scale bar = 0.5 mm. c, d LFB staining revealed demyelination in the injection side of TgM83 + AAVhSNCA, but not in WT + AAVhSNCA. Myelin is quantified as fold change relative to the contralateral (non-injection) side in WT and TgM83

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Acta Neuropathologica Communications

ISSN: 2051-5960

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