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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: IL13RA2-integrated genetically engineered mouse model allows for CAR T cells targeting pediatric high-grade gliomas

Fig. 1

IL13RA2 shows heterogenous expression in human DIPG. (A) IL13RA2 gene expression in pediatric brain tumors from Gump database was analyzed using GlioVis (http://gliovis.bioinfo.cnio.es/). Tukey’s Honest Significant Difference (HSD) was performed to compare IL13RA2 gene expression between pediatric tumors. Significance was denoted in the graph by one asterisk (*) where p < 0.05, two (**) where p < 0.01, and three (***) where p < 0.001. (B) IL13RA2 histopathological scores of post-mortem patient samples. (C) Representative images of each IL13RA2 histopathological score in post-mortem human pDMG patient samples (top panel) and corresponding H&E stains (bottom panel). Each image includes high-power insets at low-power fields (top right hovering image)

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