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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: Tet2 loss and enhanced ciliogenesis suppress α-synuclein pathology

Fig. 4

Tet2 deletion enhances the expression of genes linked with ciliogenesis and SHH signaling. Six months after striatal αSyn PFF inoculation, we examined the cortical expression of multiple genes using qPCR, a mRNA expression of Tet1, bTet2, cTet3, dTalpid3, e, Gli1, fGli2, gGli3, and hPtch1 (n = 3–5 mice per group). Data are mean ± s.e.m., analyzed using two-sided t-test, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001

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