Fig. 3
From: Tet2 loss and enhanced ciliogenesis suppress α-synuclein pathology
Tet2 inactivation reduces αSyn pathology. Representative images (scale bar 250 µM) and quantification of pS129 αSyn pathology in the frontal cortex, striatum, and substantia nigra at a, b 3 months (n = 5–7 mice per PFF group, n = 15 mice per PBS group) and c, d 6 months (n = 11–12 mice per PFF group, n = 13–14 mice per PBS group) after αSyn PFF injection. The percentage area with pS129 αSyn immunoreactive staining was quantified using the Aiforia platform. Data are mean ± s.e.m., analyzed using two-way ANOVA with Tukey’s multiple comparisons test relative to the respective controls, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001