Fig. 2
From: High-grade astrocytoma with piloid features: a single-institution case series and literature review

Microscopic findings of HGAP to demonstrate the variable morphology with (A) smear preparation showing long delicate piloid processes and admixed Rosenthal Fibers, (B) a mildly to moderately cellular region (C) higher power view of scattered eosinophlic granular bodies and Rosenthal fibers, (D) areas of oligodendroglial morphology, (E) foci demonstrating highly atpical cells with bizarre nuclear atypia, F), extensive microvascular/glomeruloid proliferation, G) foci of necrosis, and H) loss of nuclear expression of ATRX within the atypical tumor cells with appropriate internal positive control showing retained expression in endothelial cells