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Table 4 Descriptive statistic IHC for MTCOI

From: Chromogen-based double immunohistochemical detection of mitochondrial respiratory chain deficiencies in human brain tissue

MTCOI + VDAC1

Complex IV positive neurons, %

 

Observer 1

Observer 2

 

PFC

OC

CA4

CC

PFC

OC

CA4

CC

POLG1

97.89

97.60

NA

84.26

99.81

99.27

NA

88.61

POLG2

93.77

NA

99.14

83.61

96.64

NA

97.30

87.79

POLG3

95.74

95.09

94.86

91.30

95.74

94.55

98.21

91.57

Mean ± SD

95.80 ± 2.06

96.35 ± 1.77

97.00 ± 3.03

86.39 ± 4.26

97.40 ± 2.14

96.61 ± 3.34

97.76 ± 0.64

89.32 ± 1.99

Control1

99.60

99.26

99.46

99.16

99.82

99.67

98.82

95.18

Control2

100

100

99.47

99.11

100

100

98.42

100

Control3

100

100

99.47

99.42

99.71

99.90

99.73

99.61

Mean ± SD

99.87 ± 0.23

99.75 ± 0.43

99.47 ± 0.01

99.42 ± 0.50

99.84 ± 0.15

99.86 ± 0.17

98.99 ± 0.67

98.26 ± 2.68