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Table 3 Descriptive statistic IHC for NDUFS4

From: Chromogen-based double immunohistochemical detection of mitochondrial respiratory chain deficiencies in human brain tissue

NDUFS4 + VDAC1

Complex I positive neurons, %

Observer 1

Observer 2

PFC

OC

CA4

CC

PFC

OC

CA4

CC

 

POLG1

90.14

55.73

NA

22.08

91.17

55.64

NA

31.21

 

POLG2

53.91

NA

51.69

45.78

63.33

NA

47.69

50.41

 

POLG3

66.52

73.53

56.58

33.85

63.12

59.88

57

66.52

 

Mean ± SD

70.10 ± 18.39

64.63 ± 12.59

54.14 ± 3.46

33.90 ± 11.85

72.54 ± 16.13

57.76 ± 2.99

52.35 ± 6.58

49.38 ± 17.68

 

Control1

100

98.16

95.39

94.92

99.69

98.77

97.83

97.75

 

Control2

99.5

99.13

97.08

60.47

99.35

99.90

99.25

87.55

 

Control3

98.25

100

98.61

77.42

97.24

99.61

99.68

93.79

 

Mean ± SD

99.26 ± 0.88

99.10 ± 0.92

97.03 ± 1.61

77.60 ± 17.23

98.76 ± 1.33

99.43 ± 0.59

98.92 ± 0.97

93.03 ± 5.14

 
  1. PFC: prefrontal cortex; OC: occipital cortex; CC: cerebellar cortex