Table 2 Univariate analysis of associations of normalized molecular and immune features with overall survival. P-value was calculated using log rank sum test. Hazard Ratio (HR)> 1 indicates negative correlation with OS.
Feature | HR (95% CI) | P value |
|---|---|---|
ImmuneScore | 0.69 (0.51, 0.93) | 0.014 |
IFN-γ Index | 0.54 (0.41, 0.72) |  < 0.001 |
Expanded Immune Gene Signature | 0.59 (0.45, 0.78) |  < 0.001 |
T cell-inflamed Gene Signature | 0.57 (0.44, 0.76) |  < 0.001 |
Oxidative Phosphorylation (OXPHOS) Index | 1.16 (0.88, 1.51) | 0.292 |
MCP-Counter Cell type prediction | ||
 T cells | 0.65 (0.52, 0.83) |  < 0.001 |
 CD8 T cells | 0.78 (0.62, 0.98) | 0.035 |
 Cytotoxic lymphocytes | 0.72 (0.55, 0.94) | 0.017 |
 NK Cells | 0.71 (0.54, 0.95) | 0.019 |
 B lineage | 0.83 (0.65, 1.07) | 0.150 |
 Monocytic lineage | 0.69 (0.52, 0.92) | 0.012 |
 Myeloid dendritic cells | 0.90 (0.70, 1.14) | 0.370 |
 Neutrophils | 1.33 (0.99, 1.79) | 0.057 |
 Endothelial cells | 0.98 (0.76, 1.27) | 0.884 |
 Fibroblasts | 0.87 (0.68, 1.12) | 0.281 |