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Fig. 1  | Acta Neuropathologica Communications

Fig. 1 

From: Correlative light and electron microscopy imaging of proteinaceous deposits in cell cultures and brain tissues

Fig. 1 

H4/αS-HoTag3 cell line as a model for CLEM. A Map of the plasmid “pLV-αS-HoTag3.” The control plasmids, “pLV-αS” and “pLV-Venus-HoTag3,” share the same structure, except the gene sequence is replaced with either αS or Venus-HoTag3, respectively. B Schematic representation of the establishment of the H4/αS-HoTag3 cell model. H4/αS and H4/Venus-HoTag3 cells were developed using the corresponding control plasmids. C Immunofluorescence staining confirms a high proportion of phosphorylated αS (Ser129) inclusions in H4/αS-HoTag3 cells, while these inclusions were absent in the two control cell lines. Scale bars are included in each individual image

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Acta Neuropathologica Communications

ISSN: 2051-5960

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