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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: Structural and functional studies of the VAPB-PTPIP51 ER-mitochondria tethering proteins in neurodegenerative diseases

Fig. 2

Domain structure of human VAPB, VAPA and PTPIP51 with amino acid numbers indicated (the shorter 249 amino acid VAPA isoform is shown). VAPB and VAPA MSP and coiled-coil domains are shown along with their C-terminal transmembrane ER targeting sequences (TM). PTPIP51 N-terminal transmembrane mitochondrial targeting sequence (TM), coiled-coil domain, FFAT motif (VYFTASS) and C-terminal tetratricopeptide repeat domain are all shown

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