Fig. 6

Immunohistochemical tissue examination results for the investigation of immune cell distribution in the control and CLND groups. (a) CLND in animal brain sections marked with CD4 and CD11c in the ventricle-induced capsule (VIC) reveals immune cell infiltration (red arrows). The number of infiltrating immune cells increased over time from 2 weeks (2 W) to 8 weeks (8 W). (b) The image from each brain section represents dendritic cells (DCs) with a diameter larger than 1.5 μm, marked by red circles. DC count mainly increased in the white matter (WM)