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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Blocking peptidyl arginine deiminase 4 confers neuroprotective effect in the post-ischemic brain through both NETosis-dependent and -independent mechanisms

Fig. 1

PAD4 levels in the brain tissue and serum following transient MCAO (A) Schematic representation of the cortical core and penumbra regions of the post-ischemic brain. (B-C) PAD4 protein levels in the cortical penumbra (B) and cortical core (C) were measured by immunoblotting at 3, 6, 12, 24, 48, and 96 h post-surgery. (F) PAD4 protein levels in the serum were assessed by immunoblotting at 3, 6, 12, 24, 48, and 96 h post-surgery. (D, E, G) Quantification of PAD4 protein levels from immunoblots. Data are presented as the mean ± SEM (n = 4). * p < 0.05, ** p < 0.01, *** p < 0.001 compared to sham-operated controls

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Acta Neuropathologica Communications

ISSN: 2051-5960

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