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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Personalising glioblastoma medicine: explant organoid applications, challenges and future perspectives

Fig. 1

The History of 3D Brain Tumour Model Development. A timeline illustrating the evolution of various 3D preclinical models in GBM (A). Models include: PDOs (B), genetically engineered models (C), co-culturing models (D), bio-printed organoids (E), organotypic slice cultures (F) and PDEs (G). Abbreviations: embryonic stem cell (ES cell), cerebral organoid glioma (GLICO), neoplastic cerebral organoids (neoCOR), human glioma stem cell (HGSC), mouse embryonic stem cell (MESC), glioma stem cell (GSC), human embryonic stem cell (HESC). Created with BioRender.com

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Acta Neuropathologica Communications

ISSN: 2051-5960

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