Fig. 4
From: Unraveling calcium dysregulation and autoimmunity in immune mediated rippling muscle disease
Skeletal muscle from iRMD patients shows altered expression and protein level of critical regulators of calcium flux and muscle relaxation. A Heatmap showing expression of PLN, PMCA, and SERCA1 in iRMD patient skeletal muscle biopsies compared to non-disease controls. B Immunofluorescent staining of iRMD skeletal muscle compared to non-disease controls. *p < 0.05, **p < 0.01. Scale bars: PLN = 50um, PMCA = 10um, SERCA1 = 50um