Table 1 Genetic alterations in the left parietal primary, left parietal recurrent and left frontal tumors
Left Parietal Tumor Resection* | Left Parietal Recurrent Tumor Resection | Left Frontal Tumor Resection | |||
|---|---|---|---|---|---|
Surgical Pathology | Surgical Pathology | NGS (Columbia Solid Tumor Panel) | Surgical Pathology | NGS (CARIS) | |
IDH1/2 mutation | Negative (IHC) | Negative (IHC) | Negative | Negative (IHC) | Negative |
BRAFV600E | Positive (IHC) | Positive (IHC) | Positive | Negative (IHC) | Negative |
TERT promoter mutation | Positive (Targeted NGS) | Positive (Targeted NGS) | Positive | Positive (Targeted NGS) | Positive |
CDKN2A/B deletion | Negative (FISH) | - | - | - | Negative |
EGFR Amplification | Negative (FISH) | Negative (FISH) | Negative | Negative (FISH) | Negative |
MGMT methylation | Partial | - | - | Positive | Positive |
NF1 | - | - | Negative | - | Negative |
PTEN | - | - | Negative | - | Negative |