Fig. 1

Correlation matrix between quantitative imaging and immunology variables. The respective r values of significant correlations are depicted. Only r values with a significant p-value (p < 0.05) are shown. Each r value is colored according to a specific value (e.g. an r value of −0.4 is colored in light green). The reference colors of each value can be seen on the right side of the figure. They are based on the respectively appropriate statistical correlation test depending on the nature of the variable pair (see Methods) and cover all variable types apart from categorical imaging variables (where no correlation can be calculated from a statistical point of view and which are thus analyzed in the subsequent section). CD: cluster of differentiation, neg: negative, EM: effector memory, dif: differentiated, CM: central memory, NKT: natural killer T cells, Tregs: regulatory T cells, Th: T helper cells, HLA-DR: human leukocyte antigen-DR isotype, MDSC: myeloid-derived suppressor cells, IFNg: interferon gamma, mRNA: messenger ribonucleic acid, PBMC: peripheral blood mononuclear cell, IL: interleukin, ROR-gt: RAR-related orphan receptor gamma, FOXp3: forkhead box P3, TGFb: transforming growth factor beta, CET: contrast enhancing tumor, nCET: non-contrast enhancing tumor, FLAIR: fluid attenuated inversion recovery