Fig. 2

RGC loss in glaucomatous donors observed by loss of RBPMS positive cells. A Loss of RGCs in peripheral retina and macula was observed in glaucomatous donors; arrows indicate RBPMS positive cells. B Scatter dot plot represents the individual values of RBPMS-positive RGCs (RBPMS + RGCs) for non-glaucomatous (n = 16) and glaucomatous donor tissues (n = 21). Quantitative analysis demonstrated a 54% reduction in RBPMS + RGCs in glaucomatous temporal peripheral retina. Horizontal bars indicate mean ± standard deviation. ****p < 0.0001, unpaired t-test