Fig. 4

Temporal analysis of microbiota between C57Ola_G93A and 129Sv_G93A mice. Beta diversity, as well as DESeq2 and PICRUSt2 analysis, were conducted at the pre-symptomatic stage (PS) in panels A, B, and C; at disease onset (OS) in panels D, E, and F; and during the symptomatic stage (SY) in panels G, H, and I. LDA = linear discriminant analysis