Fig. 8

Higher levels of angiogenic cells within the tumor microenvironment are associated with worse 5-year survival in TCGA samples. Kaplan–Meier curves are stratified by the median percentile of angiogenic cells where if a sample is above the median, it is assigned to the “hot” (red) strata while the remaining is assigned to the “cold” (blue) strata. Individual models were run for each tumor type: A GBM angiogenic hot (n = 96, median angiogenic proportion = 4.7) versus GBM angiogenic cold (n = 32, median angiogenic proportion = 1.5), B OLG angiogenic hot (n = 62, median angiogenic proportion = 3.3) versus OLG angiogenic cold (n = 104, median angiogenic proportion = 1.6) and C AST angiogenic hot (n = 57, median angiogenic proportion = 3.5) versus GBM angiogenic cold (n = 80, median angiogenic proportion = 1.5)