Fig. 3

Genomic context of CpGs utilized in GIMiCC. A–C The methylation level of representative CpGs from GIMiCC libraries at functionally relevant genes. D–F Enrichment analysis testing for the odds of the DMCs of the GBM L0 (D), AST L0 (E), and all other deconvolution layers (F) being in a CpG island, shore, shelf, or open sea region. G–I Enrichment analysis testing for the odds of the DMCs of the GBM L0 (G), AST L0 (H), and all other deconvolution layers (I) being within a particular gene regulatory element. N north, S south, UTR untranslated region, TSS transcriptional start site