Fig. 1
From: A minimally invasive biomarker for sensitive and accurate diagnosis of Parkinson’s disease
Representative ThT Fluorescence Curves of αSyn RT-QuIC Assays of Serum or Saliva Samples. A. Representative curves of ThT fluorescence readings over time for αSynD RT-QuIC assays of serum samples from 10 PD and 10 HC subjects. B. Representative curves of ThT fluorescence readings over time for αSynD RT-QuIC assays of saliva samples from 10 PD and 10 HC subjects. All samples were coded and blinded for the RT-QuIC assays. The ThT fluorescence readings at the endpoint (93.35 h) were normalized to percentages of the maximal fluorescence reading (260,000) and used to measure the relative αSynD seeding activities in the respective samples. Orange lines: curves for PD samples; black lines: curves for HC subjects