Skip to main content
Fig. 6 | Acta Neuropathologica Communications

Fig. 6

From: Mapping the glial transcriptome in Huntington’s disease using snRNAseq: selective disruption of glial signatures across brain regions

Fig. 6

The molecular co-chaperone BAG3 is upregulated in HD microglia in a separate cohort. A-B. Double in situ hybridisation (A) on a separate human brain tissue cohort showing an increase (B) in microglia (ITGAM+, red) expressing BAG3, green. Arrow for double-positive cell. Plot shows median and range. (Welch Two Sample t-test, p-value = 0.023). C-D. Double in situ hybridisation (C) showing OPCs (PDGFRa+, red) expressing BAG3, green (D). Plot shows median and range (Wilcoxon rank sum test, p-value = 0.1). DAPI-stained nuclei coloured blue in images

Back to article page

Acta Neuropathologica Communications

ISSN: 2051-5960

Contact us