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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: Evaluation of Rho kinase inhibitor effects on neuroprotection and neuroinflammation in an ex-vivo retinal explant model

Fig. 4

Y-33075 and H-1152 prevent astrogliosis in retinal explants. a Representative confocal images of retinal explant cryosections in culture at DEV 0 and for the control solvent DEV 4 and treated DEV 4 (50 µM Y-33075, 100 µM H-1152, and 500 µM Y-27632) groups immunolabeled with GFAP (green) at 40 × magnification (n = 6 per group). Scale bar = 100 µm. b Gfap gene expression analysis in retinal explants at DEV 0 and DEV 4. Unpaired t-test test was performed between the control solvent and each other group. Error bars represent the standard error of the mean. *p < 0.05, ***p < 0.005

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