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Fig. 3 | Acta Neuropathologica Communications

Fig. 3

From: TwinF interface inhibitor FP802 prevents retinal ganglion cell loss in a mouse model of amyotrophic lateral sclerosis

Fig. 3

FP802 restores deregulated retinal gene expression in the SOD1G93A ALS mouse model. mRNA levels of Bdnf, cFos, Npas4 and Inhibin beta A were assessed by RT q-PCR in WT, SOD1G93A vehicle-treated, and SOD1G93A FP802-treated mice at 20 weeks. Statistical test: one-way analysis of variance (ANOVA) with post-hoc Tukey’s multiple comparisons test. n, WT = 9; SOD1G93A 20W (Veh) = 12; SOD1G93A 20W (FP802) = 11. Single eyes per mouse. ∗p < 0.05, ∗∗p < 0.01

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Acta Neuropathologica Communications

ISSN: 2051-5960

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