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Table 1 Sample sizes for all experiments

From: Oral nicotinamide provides robust, dose-dependent structural and metabolic neuroprotection of retinal ganglion cells in experimental glaucoma

Group abbreviation

Group descriptor

Animal number

Retina number

Total number of RGCs

Mean RGC number/retina ± SD

C.NT

Control normotensive

11

22

182

16.81 ± 2.77

NT.LNAM

Normotensive low dose NAM

6

12

115

19.16 ± 3.81

NT.HNAM

Normotensive high dose NAM

6

12

113

18.83 ± 2.74

G.HT

Glaucoma injected control

11*

11

83

9.45 ± 3.60

N.HT

Glaucoma uninjected control

11*

11

66

7.72 ± 2.80

Proph.G.HT.LNAM

Prophylactic low dose NAM glaucoma injected

6*

6

54

10 ± 2.87

Proph.N.HT.LNAM

Prophylactic low dose NAM glaucoma uninjected

6*

6

40

6.66 ± 2.56

Proph.G.HT.HNAM

Prophylactic high dose NAM glaucoma injected

12*

12

136

13 ± 3.41

Proph.N.HT.HNAM

Prophylactic high dose NAM glaucoma uninjected

12*

12

102

9.1 ± 3.76

Int.G.HT.LNAM

Intervention low dose NAM glaucoma injected

6*

6

79

13 ± 4.6

Int.N.HT.LNAM

Intervention low dose NAM glaucoma uninjected

6*

6

62

11.14 ± 2.82

Int.G.HT.HNAM

Intervention high dose NAM glaucoma injected

12*

12

104

11.07 ± 2.12

Int.N.HT.HNAM

Intervention high dose NAM glaucoma uninjected

12*

12

107

10.41 ± 3.43

  1. *Injected and uninjected retinas were taken from the same animal
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Acta Neuropathologica Communications

ISSN: 2051-5960

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