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Table 2 Test set-based accuracy, F score, and AUC of the top five ML classifiers for subgroup classification of samples based on the expression of 67 m6A-lncRNA genes

From: Systematic transcriptomic analysis of childhood medulloblastoma identifies N6-methyladenosine-dependent lncRNA signatures associated with molecular subtype, immune cell infiltration, and prognosis

 

Discovery cohort

Validation cohort

Class: WNT

Class: SHH

Class: Grp3

Class: Grp4

Multi-class AUC

Class: WNT

Class: SHH

Class: Grp3

Class: Grp4

Multi-class AUC

GLMNET

0.96

1

0.9333

0.988

0.97

0.82873

0.9255

0.7959

0.9206

0.88

SVM

0.96

0.9796

0.9655

0.988

0.988

0.82222

0.9276

0.8

0.9231

0.87

LDA

1

1

1

1

1

0.8306

0.9038

0.7744

0.885

0.86

XGBOOST

0.96

0.9583

0.8571

0.9647

0.955

0.82418

0.9155

0.8127

0.9148

0.88

GBM

0.96

0.9362

0.8387

0.9639

0.955

0.83243

0.9026

0.787

0.8976

0.87

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Acta Neuropathologica Communications

ISSN: 2051-5960

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