Skip to main content
Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: Genetic and pathophysiological insights from autopsied patient with primary familial brain calcification: novel MYORG variants and astrocytic implications

Fig. 5

Immunohistochemical findings of caudate head of patient F1-II-1. Pronounced mineralization region (A) and area without mineralization (B) in the caudate head. Astrocytic cell bodies (arrows) appear enlarged, accompanied by shortening, and distortion processes (C) in the region (A). The morphology of astrocytes in the region (B) remains preserved (D). AQP4 immunoreactivity is decreased (E) in the region (A), compared to that (F) in the region (B). Iba1 immunoreactive microglia surrounds the mineralized capillary (arrow, G) in the area (A). Iba1 immunoreactive microglia attaches the capillary wall (arrow, H) in the region (B). Staining: A, B, von Kossa; C, D, anti-glial fibrillary acid protein antibody; E, F, anti-AQP4 antibody; G, H, anti-Iba1 antibody. Scale bar: A-F, 20 μm; G–H, 10 μm

Back to article page

Acta Neuropathologica Communications

ISSN: 2051-5960

Contact us