Fig. 1

Distribution of the proximal MYC network (PMN) somatic alterations over the TCGA samples. A Percentages of samples with copy-number gains (leftmost), losses (middle), and mutations (rightmost) per gene in the PMN, each row corresponds to a molecular grade (in increasing grade). B Oncoprint for the PMN somatic alterations. C Bar plot displaying the percentages of samples with any somatic alteration in the PMN (“PMN-hit %”) by increasing grade, demonstrating increasing trend