Retinal peri-arteriolar versus peri-venular amyloidosis, hippocampal atrophy, and cognitive impairment: exploratory trial

Table 5 Pearson’s r correlations between perivascular AP and cognitive domains

Vascular type		RCFT-Copy (Z Score) n = 18–21		ACS-TOPF (Z Score) n = 21–25		CVLT-II Long Delay (Z-Score) n = 22–26		Trails A paper-and-pencil (Z-score) n = 21–25
Vascular type		r	P	r	P	r	P	r	P
Perivascular AP	Total	− 0.18	ns	0.07	ns	− 0.03	ns	− 0.26	ns
	Primary Br	0.25	ns	0.20	ns	0.46	0.017	0.18	ns
	Primary Br—main	0.09	ns	0.35	ns	0.43	0.028	0.11	ns
	Primary Br—small	0.31	ns	0.13	ns	0.44	0.024	0.20	ns
	Secondary Br	− 0.38	ns	− 0.27	ns	− 0.41	0.036	− 0.40	0.047
	Secondary Br—main	− 0.31	ns	− 0.06	ns	− 0.10	ns	− 0.47	0.02
	Secondary Br—small	− 0.32	ns	− 0.31	ns	− 0.47	0.014	− 0.25	ns
	Tertiary Br	− 0.28	ns	0.06	ns	− 0.40	0.046	− 0.30	ns
Peri-Venular AP	Total	− 0.45	0.043	− 0.14	ns	− 0.21	ns	− 0.42	0.039
	Primary Br	0.16	ns	0.19	ns	0.28	ns	0.16	ns
	Primary Br—main	0.15	ns	0.29	ns	0.27	ns	0.18	ns
	Primary Br—small	0.14	ns	0.09	ns	0.24	ns	0.11	ns
	Secondary Br	− 0.34	ns	− 0.38	ns	− 0.51	0.0091	− 0.31	ns
	Secondary Br– main	0.02	ns	0.07	ns	− 0.20	ns	− 0.32	ns
	Secondary Br—small	− 0.44	ns	− 0.49	0.015	− 0.49	0.014	− 0.17	ns
	Tertiary Br	− 0.40	ns	− 0.17	ns	− 0.45	0.036	− 0.47	0.037
Peri-Arteriolar AP	Total	0.05	ns	0.19	ns	0.09	ns	− 0.10	ns
	Primary Br	0.24	ns	0.17	ns	0.50	0.010	0.15	ns
	Primary Br—main	− 0.02	ns	0.32	ns	0.53	0.005	− 0.02	ns
	Primary Br—small	0.24	ns	0.12	ns	0.44	0.030	0.13	ns
	Secondary Br	− 0.30	ns	− 0.12	ns	− 0.34	ns	− 0.31	ns
	Secondary Br—main	− 0.43	ns	− 0.10	ns	− 0.09	ns	− 0.44	0.027
	Secondary Br—small	− 0.17	ns	− 0.10	ns	− 0.37	ns	− 0.18	ns
	Tertiary Br	0.06	ns	0.17	ns	− 0.32	ns	− 0.05	ns

Bolded values are significant after Holms-Bonferroni multiple comparisons correction
AP Amyloid plaque, Br Branch, RCFT Rey Complex Figure Test and Recognition Trial, ACS-TOPF test of Premorbid Functioning, CVLT California Verbal Learning Test

ISSN: 2051-5960