Fig. 4

Correlations between retinal perivascular amyloid plaque distribution with cognitive and neuroimaging measures. Pearson’s r correlation analyses between retinal perivascular AP count and CDR (A), MOCA (B), RCFT-copy registration (C), Trail A-paper and pencil (D), ACS-TOFF (E), CVLT-II Long delay (F), hippocampal volume (G) and white matter hyperintensities lesions (H). AP, Amyloid plaques; CDR, Clinical dementia rating; MOCA, Montreal cognitive assessment; RCFT, Rey Complex Figure Test and Recognition Trial; ACS-TOPF, test of Premorbid Functioning; CVLT, California Verbal Learning Test; HV, hippocampal volume, WMH, White matter hypertensity; 2° Br, secondary branches; 3° Br, tertiary branches. Color code for vessel type: purple—perivascular; blue—peri-venular; red—peri-arteriolar