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Table 1 Demographic characteristics of the IMABio3 cohort

From: Mitochondrial alterations in fibroblasts from sporadic Alzheimer's disease (AD) patients correlate with AD-related clinical hallmarks

Group

# of patients

Age

Gender

MMSE

CDR-SOB

PiB-GCI

CTRL

9

51–81

4F/5 M

29.3 ± 0.86

0

1.43 ± 0.30

AD-MCI

11

52–79

5F/6 M

24.3 ± 2.97

2.50 ± 1.07

2.75 ± 0.57

AD-D

9

51–81

8F/1 M

16.5 ± 3.36

7.21 ± 0.69

3.00 ± 0.54

  1. The CDR-SOB (Clinical Dementia Rating, Scale Sum of Boxes) scale indicates the severity of dementia; no dementia (CDR = 0). The maximum score for the Mini-Mental State Examination (MMSE) is 30, with lower scores associated with greater cognitive deterioration
  2. CTRL control; AD-MCI Alzheimer’s disease patients with mild-cognitive impairment; AD-D Alzheimer’s disease patients with dementia; F female; M male; CDR-SOB clinical dementia rating sum of the boxes; PiB-GCI 11C‐labelled Pittsburgh compound B, Global cortical index