Fig. 5
From: Cryo-EM structures reveal tau filaments from Down syndrome adopt Alzheimer’s disease fold
PHF and SF cross-section views of the tau filament cryo–electron microscopy structures determined from four DS cases. The relative percentage of the segments for the reconstructions is indicated with the final resolution and grid preparation method. In the 36 years old case, a minor percentage refined to show a conformation similar to CTE type II filaments (indicated). However, an atomic model was unable to be determined due to the low resolution and small dataset size