Fig. 9

Summary of A contrast sensitivity and B acuity in 5xFAD B6J mice that were either untreated (n = 5) or treated with DMSO vehicle (n = 5) or R-carvedilol (n = 5). Black horizontal line indicates P < 0.05 (two-tailed, linear mixed-model analysis; mean ± 95% CI). Individual data points represent the measured value for each mouse. Potential strain differences in both indices did not depend on which direction the grating moved, and means did not differ between directions so averages over both directions are presented