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Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: Biomarker evidence of early vision and rod energy-linked pathophysiology benefits from very low dose DMSO in 5xFAD mice

Fig. 5

Summary of changes in WT (n = 5) vs. 5xFAD (n = 10) B6J mice. A Representative OCTs of light-adapted B6J mice in superior outer retina (left panel). Representative reflectivity profiles in the direction indicated by the green arrow, in superior retina (right panel). ELM-RPE region is indicated by the horizontal line, MCP/AR is shown in pink. B MCP/AR increased in 5xFAD mice suggesting inefficient mitochondria. Values did not depend on side, and means did not differ between sides so average over side are presented. C ELM-RPE contracted in 5xFAD mice suggesting hyperactivity

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Acta Neuropathologica Communications

ISSN: 2051-5960

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