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Table 2 Clinicopathologic characteristics

From: NTRK-fused central nervous system tumours: clinicopathological and genetic insights and response to TRK inhibitors

Patient characteristics

Children

Adults

Total No. (N = 11)

6

6

Sex

  

  Male

1

4

  Female

5

2

Ag, median, years

  

  ≤ 3

4

0

  Teenage

2

0

  Young adult < 35

0

2

  Adult ≥ 35

0

4

Location

  

  Hemisphere

3

4

  Lateral ventricle or thalamus

2

0

  Cerebellum

0

2

  Spinal cord

1

0

Fusion genes

  

  NTRK2

4

6

  NTRK1

2

0

Treatment

  

  Operation only

2

4

  OP+CCRT

1

0

  OP+CCRT+TMZ

0

1

  OP+ NTRK inhibitor

1

0

  OP+Adjuvant Tx+NTRK inhibitor

2

1