Fig. 3

Patient #12 had the BCR::NTRK2 fusion. A, B T2-weighted turbo spin‒echo (TSE) and T2 FLAIR images showing a hyperintense mass in the thalamus and bifrontal area with peritumoral oedema. C The tumour was composed of oligodendroglioma-like clear cells with microvascular proliferation and pseudopalisading necrosis. D and E Diffuse positivity for TRK and Olig2 was observed in the cytoplasm and nuclei, respectively, of tumour cells. F The Ki-67 labelling index was high (88.4%). G The Arriba plot revealed the in-frame fusion between the BCR gene and NTRK2 gene (scale bar, F: 50 μm)