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Fig. 3 | Acta Neuropathologica Communications

Fig. 3

From: Longitudinal multiomics analysis of aggressive pituitary neuroendocrine tumors: comparing primary and recurrent tumors from the same patient, reveals genomic stability and heterogeneous transcriptomic profiles with alterations in metabolic pathways

Fig. 3

Panels A and C bubble plot of altered metabolic pathways in gonadotroph PitNET showing how the transcription factors PPARG, ZBTB3 and SREBF1-2 can potentially regulate the expression of metabolic genes expressed in these pituitary neuroendocrine tumors. Panel B bubble plot of dysregulated pathways in metastatic corticotroph PitNET, and panel D gene regulatory networks in metastatic corticotroph PitNET Panel E bubble plot of dysregulated pathways in somatotroph PitNET and panel G gene regulatory network of somatotroph PitNET. Panel F bubble plot of dysregulated pathways in silent corticotroph PitNET and panel H gene regulatory network of silent corticotroph PitNET

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Acta Neuropathologica Communications

ISSN: 2051-5960

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