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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: A longer time to relapse is associated with a larger increase in differences between paired primary and recurrent IDH wild-type glioblastomas at both the transcriptomic and genomic levels

Fig. 2

Associations of TTR with the differences between paired P-R GBMs at the transcriptomic and genomic levels. A-B Comparisons of the gene expression differences (measured by the RMSE) (A) and the effects of differential expression (measured by the absolute value of log2 transformed fold change) (B) between paired P-R GBMs for patients in the three TTR groups: patients with TTR ≤ 6 months, TTR of 7–12 months, and TTR < 12 months. C Comparisons of the TMB values (mutations/Mb) between paired P-R GBMs for all patients (left) and patients in the three TTR groups (right). D Comparisons of various types of gene mutation features for primary and recurrent GBMs in the three TTR groups. For (A)-(C), P values were evaluated using Wilcoxon signed rank test. For (D), P values were evaluated using one proportion Z-Test. pGBM, primary GBM. rGBM, recurrent GBM

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Acta Neuropathologica Communications

ISSN: 2051-5960

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