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Table 3 P value and 95% CI per comparison of conditions in the retinal ganglion cell analysis

From: Intravitreal MPTP drives retinal ganglion cell loss with oral nicotinamide treatment providing robust neuroprotection

Retinal ganglion cells

P value

95% CI

RBMPS+ cell soma count

Naïve control—vehicle control

1.000

[− 6.708, 8.691]

Naïve control—MPTP 5 mg/ml 7 days after injection

0.002**

[− 14.718, − 3.028]

Naïve control—MPTP 5 mg/ml 14 days after injection

0.010**

[− 14.603, − 1.699]

Naïve control—MPTP 5 mg/ml 21 days after injection

 < 0.001***

[− 19.019, − 6.116]

Naïve control—MPTP 50 mg/ml 7 days after injection

 < 0.001***

[− 21.536, − 5.116]

Naïve control—MPTP 50 mg/ml 14 days after injection

0.018*

[− 19.525, − 1.537]

Naïve control—MPTP 50 mg/ml 21 days after injection

 < 0.001***

[− 25.325, 7.337]

  1. Significance: *P < 0.05, **P < 0.01, ***P < 0.001