Fig. 7

Sturge-Weber brain microenvironment. Tiling image (top) of Sturge-Weber brain leptomeninges labeled for MRC1 (green), αSMA (grey), UEAI (red) and nuclei counterstaining for DAPI (blue). Zoom insert shows vessels with and without αSMA layer surrounded by MRC1⁺ cells in the perivascular space. Scale bar = 200 µm. The illustration (bottom) shows mural cells (αSMA, calponin, NG2 and desmin) around the endothelial cells. MRC1, CD163, LYVE1, and CD68 macrophages in the perivascular space along with the neurons and microglia cells