Fig. 5

a Barplot demonstrating predicted relative proportions of MB cell types in bulk primary and relapse tumor gene expression profiles. Thick black lines delimitated each primary-relapse pair. b, c Boxplots of difference between MB SHH primary and relapse tumors in proportions of undifferentiated progenitors B1 (b) and differentiated neuron-like cells C1 (c). d, e Boxplots of difference between MB G4 primary and relapse tumors in proportions of cell cycle enriched A1 (d) and differentiated neuron-like cells C1 (e)