Fig. 1

A Sleep fragmentation protocol time-line. B Typical hypnograms reporting sleep oscillations during baseline 24 h recording (top) and during fragmentation protocol (bottom). Thick lines indicate the dark period. C Total sleep time is represented as an average of the recordings. D The variation in the percentages relating to wakefulness, NREM sleep, and REM sleep. The two genotypes were compared for the three variables in basal and fragmentation conditions. NF not fragmented mice, F fragmented mice. The data are mean standard error of the mean (SEM), n = 3 per strain