Figure 6

Cartoon depicting the structure of the DHX57:TMEM178:MAP4K3 fusion. A complex microhomology-mediated rearrangement of exons 1–12 of DHX57 (blue), exons 2–4 of TMEM178 (green) and exons 13–34 of MAP4K3 (orange) was confirmed by direct sequencing. Regions of microhomology are highlighted in grey.